HZ does not often appear after the administration of other kinds of vaccinations. They received oral acyclovir for 1 week, and all vesicles become dry without post-herpetic neuralgia. HZ was diagnosed later when the typical clinical presentation of HZ as grouped vesicles was present over left T11 and right T10 dermatomes, respectively. This 71-year-old man had painful itchy grouped vesicles over left T8 dermatome area since 2 days after receiving the first dose of COVID-19 vaccine.Ĭase 2 and 3: Another 2 healthy men (46- and 42-years-old) developed pain and itch over ipsilateral flank at 2 days and 7 days following receiving their first dose of AZD1222 vaccine. He received oral acyclovir for 1 week, and all vesicles become dry without obvious complication. HZ involving left T8 dermatome was diagnosed. Two days later, grouped erythematous papules and vesicles appeared on his left flank with itching and pain ( Figure 1). We wish to report three cases from Taiwan.Ĭase 1: A 71-year-old healthy man, denied systemic disease, received his first injection of Moderna COVID-19 vaccine. 6 Before this manuscript was written, there has been no report regarding the phenomenon of about HZ following injection of AZD1222 vaccine. According to the multinational placebo-controlled clinical trial conducted in Brazil, South Africa and the UK, no event of HZ followed by AZ vaccination was reported. 1–5 The Oxford/AstraZeneca vaccine, AZD1222 ( ChAdOx1 nCoV-19) which uses a live modified chimpanzee adenovirus, has been approved and used in many European and Asian countries. There are increasing reports regarding the activation of herpes zoster (HZ) following SARS-CoV-2 mRNA vaccines ( Pfizer-BNT162b2 mRNA and Moderna mRNA-1273). Global application of vaccination is ongoing against SARS-CoV-2 (COVID-19) pandemic.
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